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SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
USERS' SCORE
Good
Based on 1 Reviews
8.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
7
Curcumin nanoparticles improve erectile function
Topically Applied Curcumin-Loaded Nanoparticles Treat Erectile Dysfunction in a Rat Model of Type-2 Diabetes.
High relevance to erectile dysfunction treatment
We explored the potential benefits of curcumin, a compound found in turmeric, for treating erectile dysfunction (ED) in a rat model of type-2 diabetes. To assess its effectiveness, we applied curcumin-loaded nanoparticles directly to the skin of diabetic rats every two days for two weeks. This method was chosen to bypass the poor absorption of curcumin when taken orally, which limits its effectiveness.
The findings revealed that applying these curcumin nanoparticles did improve erectile function in the treated rats, particularly at lower stimulation levels. We measured the erectile response by assessing pressure changes in the rats' bodies after nerve stimulation. Alongside this, we also noted changes in inflammatory markers within the corporal tissue, suggesting a potential therapeutic mechanism.
However, while the response was promising, it was significant only under certain conditions and not overwhelmingly strong. This indicates that further research is necessary to refine treatment protocols and understand any possible side effects. Overall, our study highlights the possibility of using topical curcumin as a novel treatment option for ED in patients with type-2 diabetes.
The findings revealed that applying these curcumin nanoparticles did improve erectile function in the treated rats, particularly at lower stimulation levels. We measured the erectile response by assessing pressure changes in the rats' bodies after nerve stimulation. Alongside this, we also noted changes in inflammatory markers within the corporal tissue, suggesting a potential therapeutic mechanism.
However, while the response was promising, it was significant only under certain conditions and not overwhelmingly strong. This indicates that further research is necessary to refine treatment protocols and understand any possible side effects. Overall, our study highlights the possibility of using topical curcumin as a novel treatment option for ED in patients with type-2 diabetes.
Read More
9
Curcumin enhances erectile function
Effects of a water-soluble curcumin protein conjugate vs. pure curcumin in a diabetic model of erectile dysfunction.
Study relevance to curcumin efficacy
We explored the potential benefits of water-soluble curcumin for treating erectile dysfunction (ED) in a diabetic rat model. The study involved 120 male white albino rats divided into various groups, including controls and several diabetic cohorts. Some groups received pure curcumin, while others were administered a water-soluble version of curcumin over different timeframes.
After conducting the treatments, we observed that both forms of curcumin led to improvements in erectile function, notably seen through increased intracavernosal pressure and elevated levels of certain key enzymes and genes tied to erectile signaling. However, our findings indicated that water-soluble curcumin showed greater effectiveness and longer-lasting results than pure curcumin.
Interestingly, administration of Zinc protoporphyrin was found to reduce some of the beneficial effects, which highlights the importance of understanding how different compounds can interact in the body. Ultimately, our research suggests that water-soluble curcumin could provide a promising treatment option for ED, particularly in a diabetic context.
After conducting the treatments, we observed that both forms of curcumin led to improvements in erectile function, notably seen through increased intracavernosal pressure and elevated levels of certain key enzymes and genes tied to erectile signaling. However, our findings indicated that water-soluble curcumin showed greater effectiveness and longer-lasting results than pure curcumin.
Interestingly, administration of Zinc protoporphyrin was found to reduce some of the beneficial effects, which highlights the importance of understanding how different compounds can interact in the body. Ultimately, our research suggests that water-soluble curcumin could provide a promising treatment option for ED, particularly in a diabetic context.
Read More
9
Curcumin may improve erectile function
Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function.
Examines curcumin's effectiveness
We explored the effectiveness of a novel curcumin derivative, known as NCD, in comparison to sildenafil citrate for treating erectile dysfunction. The study involved 60 male rats, including a control group and diabetic subjects, allowing us to assess various health markers related to erectile function.
Our findings revealed that after diabetes was induced, the rats experienced significant erectile dysfunction, as indicated by lowered levels of crucial biomarkers. However, with the administration of treatments including NCD, sildenafil, and their combination, we observed improvements across the board.
Notably, both the curcumin derivative alone and in tandem with sildenafil demonstrated considerable efficacy, enhancing erectile function more effectively than sildenafil alone and having a more prolonged effect. This indicates that NCD could serve as a promising alternative for improving erectile health.
Our findings revealed that after diabetes was induced, the rats experienced significant erectile dysfunction, as indicated by lowered levels of crucial biomarkers. However, with the administration of treatments including NCD, sildenafil, and their combination, we observed improvements across the board.
Notably, both the curcumin derivative alone and in tandem with sildenafil demonstrated considerable efficacy, enhancing erectile function more effectively than sildenafil alone and having a more prolonged effect. This indicates that NCD could serve as a promising alternative for improving erectile health.
Read More
Most Useful Reviews
9.5
Improved erectile dysfunction
Magic! The anti-inflammatory and vasodilatory effects are superb, significantly aiding in addressing my erectile dysfunction—a remarkable outcome!
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.6
9
Curcumin shows potential in ED rehabilitation
Curcumin slow-release membrane promotes erectile function and penile rehabilitation in a rat model of cavernous nerve injury.
Focused on curcumin effects
We explored the effects of curcumin, a compound derived from turmeric, on erectile dysfunction (ED) caused by cavernous nerve injury. This type of injury can occur during various medical procedures, posing a significant challenge for recovery.
Our study focused on a novel approach using a specially designed slow-release membrane that delivers curcumin directly to the site of injury in rats. We found that this curcumin-loaded membrane not only helped restore nerve connectivity but also improved erectile function by enhancing the expression of important proteins in the penile tissue.
Moreover, this treatment reduced the extent of tissue fibrosis, aiding in overall penile rehabilitation. While our research shows promising results for the use of curcumin in addressing ED following nerve injury, it is essential to evaluate its effectiveness thoroughly in human subjects.
This study points to curcumin's potential as a therapeutic option for those struggling with ED due to nerve damage, making it a hopeful avenue for future treatments.
Our study focused on a novel approach using a specially designed slow-release membrane that delivers curcumin directly to the site of injury in rats. We found that this curcumin-loaded membrane not only helped restore nerve connectivity but also improved erectile function by enhancing the expression of important proteins in the penile tissue.
Moreover, this treatment reduced the extent of tissue fibrosis, aiding in overall penile rehabilitation. While our research shows promising results for the use of curcumin in addressing ED following nerve injury, it is essential to evaluate its effectiveness thoroughly in human subjects.
This study points to curcumin's potential as a therapeutic option for those struggling with ED due to nerve damage, making it a hopeful avenue for future treatments.
Read More
9
Curcumin may improve erectile function
Efficacy of a novel water-soluble curcumin derivative versus sildenafil citrate in mediating erectile function.
Examines curcumin's effectiveness
We explored the effectiveness of a novel curcumin derivative, known as NCD, in comparison to sildenafil citrate for treating erectile dysfunction. The study involved 60 male rats, including a control group and diabetic subjects, allowing us to assess various health markers related to erectile function.
Our findings revealed that after diabetes was induced, the rats experienced significant erectile dysfunction, as indicated by lowered levels of crucial biomarkers. However, with the administration of treatments including NCD, sildenafil, and their combination, we observed improvements across the board.
Notably, both the curcumin derivative alone and in tandem with sildenafil demonstrated considerable efficacy, enhancing erectile function more effectively than sildenafil alone and having a more prolonged effect. This indicates that NCD could serve as a promising alternative for improving erectile health.
Our findings revealed that after diabetes was induced, the rats experienced significant erectile dysfunction, as indicated by lowered levels of crucial biomarkers. However, with the administration of treatments including NCD, sildenafil, and their combination, we observed improvements across the board.
Notably, both the curcumin derivative alone and in tandem with sildenafil demonstrated considerable efficacy, enhancing erectile function more effectively than sildenafil alone and having a more prolonged effect. This indicates that NCD could serve as a promising alternative for improving erectile health.
Read More
9
Curcumin derivative improves erectile function
Molecular signalling of a novel curcumin derivative versus Tadalafil in erectile dysfunction.
Curcumin tested but not isolated
We set out to investigate how a novel curcumin derivative (NCD), an active component of turmeric, affects erectile dysfunction (ED), particularly in comparison to tadalafil, a well-known treatment. In our study, we used ten control male rats alongside fifty diabetic male rats, dividing them into groups to evaluate various treatments, including the curcumin derivative, tadalafil, and combinations of both.
After inducing diabetes, we confirmed that the rats experienced significant ED, evidenced by a notable decrease in erectile function markers. We observed that all treatment groups showed improved erectile function. Notably, the groups receiving NCD, or NCD in combination with tadalafil, demonstrated the most significant benefits and prolonged effects.
Our findings suggest that both curcumin and its derivative are promising options for enhancing erectile function. However, we could not isolate the effects of turmeric completely due to the combined treatments with tadalafil. Ultimately, our research indicates that a curcumin derivative may offer a valuable alternative or complement to traditional ED treatments.
After inducing diabetes, we confirmed that the rats experienced significant ED, evidenced by a notable decrease in erectile function markers. We observed that all treatment groups showed improved erectile function. Notably, the groups receiving NCD, or NCD in combination with tadalafil, demonstrated the most significant benefits and prolonged effects.
Our findings suggest that both curcumin and its derivative are promising options for enhancing erectile function. However, we could not isolate the effects of turmeric completely due to the combined treatments with tadalafil. Ultimately, our research indicates that a curcumin derivative may offer a valuable alternative or complement to traditional ED treatments.
Read More
9
Curcumin enhances erectile function
Effects of a water-soluble curcumin protein conjugate vs. pure curcumin in a diabetic model of erectile dysfunction.
Study relevance to curcumin efficacy
We explored the potential benefits of water-soluble curcumin for treating erectile dysfunction (ED) in a diabetic rat model. The study involved 120 male white albino rats divided into various groups, including controls and several diabetic cohorts. Some groups received pure curcumin, while others were administered a water-soluble version of curcumin over different timeframes.
After conducting the treatments, we observed that both forms of curcumin led to improvements in erectile function, notably seen through increased intracavernosal pressure and elevated levels of certain key enzymes and genes tied to erectile signaling. However, our findings indicated that water-soluble curcumin showed greater effectiveness and longer-lasting results than pure curcumin.
Interestingly, administration of Zinc protoporphyrin was found to reduce some of the beneficial effects, which highlights the importance of understanding how different compounds can interact in the body. Ultimately, our research suggests that water-soluble curcumin could provide a promising treatment option for ED, particularly in a diabetic context.
After conducting the treatments, we observed that both forms of curcumin led to improvements in erectile function, notably seen through increased intracavernosal pressure and elevated levels of certain key enzymes and genes tied to erectile signaling. However, our findings indicated that water-soluble curcumin showed greater effectiveness and longer-lasting results than pure curcumin.
Interestingly, administration of Zinc protoporphyrin was found to reduce some of the beneficial effects, which highlights the importance of understanding how different compounds can interact in the body. Ultimately, our research suggests that water-soluble curcumin could provide a promising treatment option for ED, particularly in a diabetic context.
Read More
7
Curcumin nanoparticles improve erectile function
Topically Applied Curcumin-Loaded Nanoparticles Treat Erectile Dysfunction in a Rat Model of Type-2 Diabetes.
High relevance to erectile dysfunction treatment
We explored the potential benefits of curcumin, a compound found in turmeric, for treating erectile dysfunction (ED) in a rat model of type-2 diabetes. To assess its effectiveness, we applied curcumin-loaded nanoparticles directly to the skin of diabetic rats every two days for two weeks. This method was chosen to bypass the poor absorption of curcumin when taken orally, which limits its effectiveness.
The findings revealed that applying these curcumin nanoparticles did improve erectile function in the treated rats, particularly at lower stimulation levels. We measured the erectile response by assessing pressure changes in the rats' bodies after nerve stimulation. Alongside this, we also noted changes in inflammatory markers within the corporal tissue, suggesting a potential therapeutic mechanism.
However, while the response was promising, it was significant only under certain conditions and not overwhelmingly strong. This indicates that further research is necessary to refine treatment protocols and understand any possible side effects. Overall, our study highlights the possibility of using topical curcumin as a novel treatment option for ED in patients with type-2 diabetes.
The findings revealed that applying these curcumin nanoparticles did improve erectile function in the treated rats, particularly at lower stimulation levels. We measured the erectile response by assessing pressure changes in the rats' bodies after nerve stimulation. Alongside this, we also noted changes in inflammatory markers within the corporal tissue, suggesting a potential therapeutic mechanism.
However, while the response was promising, it was significant only under certain conditions and not overwhelmingly strong. This indicates that further research is necessary to refine treatment protocols and understand any possible side effects. Overall, our study highlights the possibility of using topical curcumin as a novel treatment option for ED in patients with type-2 diabetes.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Reviews
8.6
9.5
Improved erectile dysfunction
Magic! The anti-inflammatory and vasodilatory effects are superb, significantly aiding in addressing my erectile dysfunction—a remarkable outcome!
